Challenges and novel approaches for investigating molecular mediation
نویسندگان
چکیده
منابع مشابه
Challenges and novel approaches for investigating molecular mediation
Understanding mediation is useful for identifying intermediates lying between an exposure and an outcome which, when intervened upon, will block (some or all of) the causal pathway between the exposure and outcome. Mediation approaches used in conventional epidemiology have been adapted to understanding the role of molecular intermediates in situations of high-dimensional omics data with varyin...
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ژورنال
عنوان ژورنال: Human Molecular Genetics
سال: 2016
ISSN: 0964-6906,1460-2083
DOI: 10.1093/hmg/ddw197